Opioids And Night Sweats


Did you know that night sweats, an uncomfortable and often disruptive symptom, can be linked to opioid use? Opioids are commonly prescribed for pain relief, but they can sometimes result in unpleasant side effects, including excessive sweating during the night. In this article, we will discuss the connection between opioid use and night sweats, providing valuable insights for those affected.

🛌⚠️ Men: Night sweats can have many causes. Read out complete overview of the topic on the Causes of Night Sweats in Men: Triggers, Remedies, and FAQs

🛌⚠️ Women: Night sweats can have many causes. Read out complete overview of the topic on the Causes of Night Sweats in Women: Triggers, Remedies, and FAQs

I. Background Information

A. Definition

Night sweats are episodes of excessive sweating that occur during sleep, often leading to damp sheets and clothing. They can significantly impact a person’s rest and overall quality of life. In the context of opioid use, night sweats may be a common side effect experienced by many individuals taking these medications.

B. Prevalence

Though exact statistics are unavailable, it is known that night sweats may be a common side effect among opioid users. The prevalence of opioid-induced night sweats may vary depending on the type of opioid used, the dose, and the duration of use, among other individual factors.

C. Causes and Risk Factors

Night sweats can be a result of various factors, including medications, hormone imbalances, or underlying medical conditions. Opioid use adds another potential source to the list of causes and risk factors. Opioids can impact the body’s thermoregulation, leading to an increase in sweating, especially during nighttime. Some common risk factors for developing night sweats while taking opioids may include:

  • Higher dosages of opioids
  • Long-term opioid use
  • Concurrent use of other medications that may increase sweating
  • Discontinuation or tapering of opioids
  • Individual differences in metabolism and response to opioids

Understanding the causes and risk factors can help individuals and their healthcare providers develop effective strategies to manage and prevent night sweats related to opioid use, ultimately improving their overall well-being.

II. Symptoms and Diagnosis

A. Common Symptoms

Night sweats linked to opioid use can present a range of associated symptoms beyond the excessive sweating during sleep. Some of these common symptoms include:

  • Chills
  • Rapid heart rate
  • Disruptions in sleep patterns

B. Diagnostic Criteria

In order to determine whether opioids are the cause of the night sweats, healthcare providers follow several diagnostic steps. The diagnostic criteria may include:

  1. Medical history: A detailed discussion of the patient’s symptoms, existing health issues, medication use, and family history is essential for assessing potential contributing factors to the night sweats.
  2. Physical examination: The doctor performs a thorough physical examination to evaluate the patient’s overall health and rule out other conditions that could be causing the night sweats.
  3. Review of medications: A careful review of the patient’s current medications, including opioids, is necessary to identify possible medication-related causes of night sweats.

If you are experiencing persistent or severe night sweats along with other symptoms, it is important to consult a healthcare professional to identify the underlying cause and develop an appropriate treatment plan.

III. Treatment and Management

Addressing night sweats associated with opioid use involves a multifaceted approach that includes conventional treatments, alternative options, and lifestyle changes. Developing an appropriate management plan can help alleviate symptoms and improve overall well-being.

A. Conventional Treatments

Your healthcare provider may recommend the following treatments if opioids are determined to be the cause of your night sweats:

  1. Medication Adjustment: In consultation with your healthcare professional, adjusting the dosage or frequency of your opioid medication might help mitigate night sweats. This, however, should only be done under a doctor’s supervision to ensure safe and responsible pain management.
  2. Alternative Pain Management: Depending on your individual circumstances, a healthcare professional may suggest alternative pain management options, such as non-opioid medications or non-pharmacological interventions, to alleviate night sweats associated with opioid use.

B. Alternative Treatments

Some individuals may explore alternative treatments to manage night sweats related to opioid use:

  1. Acupuncture: Research suggests that acupuncture may be effective in reducing symptoms of night sweats for some individuals. Ensure you consult a healthcare professional before trying acupuncture to determine if it could be a suitable option for your specific situation.
  2. Herbal Remedies: Herbal treatments, such as black cohosh or sage, have been used traditionally to alleviate night sweats. Consult with a healthcare professional before introducing any herbal remedies to your treatment plan.

C. Lifestyle Changes

Adopting specific lifestyle changes can mitigate night sweats and improve overall quality of life:

  1. Sleep Environment: Maintaining a cool sleeping environment by using fans or air conditioning, as well as lightweight bedding, can help prevent night sweats.
  2. Moisture-Wicking Fabrics: Choose moisture-wicking sleepwear and bed linens to reduce dampness and discomfort associated with night sweats. These fabrics draw moisture away from the skin, keeping you dry and comfortable.
  3. Hydration: Staying well-hydrated throughout the day can help manage night sweats more effectively. Drink water regularly and avoid excessive caffeine or alcohol intake, as these can exacerbate symptoms.

IV. Complications and Long-term Effects

A. Possible Complications

Experiencing night sweats due to opioid use can result in various complications for the affected individuals. Some of these complications include:

  • Chronic sleep disruptions
  • Fatigue
  • Irritability
  • Difficulties in daily functioning

Persistent night sweats can also disrupt sleep quality, potentially leading to chronic sleep deprivation and associated issues, such as weakened immunity, mood disorders, and reduced daily functioning.

B. Long-term Effects

If night sweats caused by opioid use persist without intervention, they can have a significant impact on an individual’s long-term physical and mental health. Some of the potential long-term effects include:

  • Mood disorders, such as anxiety and depression
  • Memory impairment and cognitive decline
  • Reduced work performance and a higher risk of accidents
  • Sexual dysfunction
  • Worsened overall quality of life

Given these potential consequences, it is vital to address opioid-related night sweats and work with a healthcare provider to develop effective management and treatment strategies.

V. Prevention and Coping Strategies

A. Prevention Tips

As preventing night sweats due to opioid use can be difficult, it is essential to manage opioid use responsibly under a doctor’s guidance. Some helpful tips include:

  • Responsible opioid usage: Follow your healthcare provider’s recommendations for dosage and duration of opioid use to minimize potential side effects, including night sweats.
  • Monitor side effects: Keep a log of any side effects experienced while using opioids, including night sweats, and share this information with your healthcare provider.
  • Explore alternative pain management options: Consult with your healthcare provider about alternative pain treatments that may reduce or eliminate the need for opioid medications.
  • Manage underlying health conditions: Addressing the root cause of your pain, such as inflammation or injury, can potentially lessen your reliance on opioids.

B. Coping Strategies

To better manage night sweats and the impact on your overall well-being, consider the following coping strategies:

  • Seek support: Reach out to healthcare providers, therapists, or support groups to share your experiences and find resources for managing night sweats related to opioid use.
  • Develop a calming bedtime routine: Engage in relaxation techniques, such as deep breathing exercises, gentle stretching, or meditation, to encourage a restful sleep environment and reduce night sweat symptoms.
  • Stay informed: Educate yourself on the relationship between opioids and night sweats by consulting reputable resources, such as medical professionals or accredited online sources.
  • Maintain a healthy lifestyle: Focus on overall health by eating a balanced diet, engaging in regular exercise, and managing stress to potentially reduce the frequency or severity of night sweats.

VI. Frequently Asked Questions

Can pain medication cause night sweats?

Yes, pain medication, particularly opioids, can cause night sweats due to their effects on the central nervous system and the body’s temperature regulation mechanisms.

What drugs make you sweat at night?

Drugs that can make you sweat at night include opioids, antidepressants, hormone replacement therapy, diabetes medications, corticosteroids, and some blood pressure medications.

How do you stop excessive sweating from opioids?

To stop excessive sweating from opioids, consult with your healthcare provider to discuss potential medication adjustments or alternative treatments, stay well-hydrated, and maintain a cool and comfortable environment, particularly during sleep.

What are opioid withdrawal symptoms?

Opioid withdrawal symptoms include muscle aches, restlessness, anxiety, sweating, diarrhea, nausea, vomiting, rapid heart rate, high blood pressure, and insomnia.


If you’re experiencing night sweats while using opioids, it’s essential to consult with a healthcare professional to develop an appropriate treatment and management plan. By addressing opioid-related night sweats, you can improve your well-being and take back control of your health.

Medical Disclaimer: This article is for informational purposes only and should not be considered professional medical advice. It is always recommended to consult with a healthcare professional before making any changes to your treatment plan, diet, or lifestyle. StopTheNightSweats.com is not responsible for any actions taken as a result of the information provided in this article.


  1. Gudin JA, Laitman A, Nalamachu S. Opioid Related Endocrinopathy. Pain Med. 2015 Oct;16 Suppl 1:S9-15. doi: 10.1111/pme.12926. PMID: 26461076.